Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein Tyrosine Phosphatases » Receptor-Like Protein Tyrosine Phosphatases » Receptor-Like Protein Tyrosine Phosphatases, Class 1 » Leukocyte Common Antigens
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Esterases » Phosphoric Monoester Hydrolases » Protein Tyrosine Phosphatases » Receptor-Like Protein Tyrosine Phosphatases » Receptor-Like Protein Tyrosine Phosphatases, Class 1 » Leukocyte Common Antigens
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptor-Like Protein Tyrosine Phosphatases » Receptor-Like Protein Tyrosine Phosphatases, Class 1 » Leukocyte Common Antigens
Description
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons. MeSH
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