Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Amyloid » Amyloidogenic Proteins » Amyloid beta-Protein Precursor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Amyloid beta-Protein Precursor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Protein Precursors » Amyloid beta-Protein Precursor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Proteinase Inhibitory Proteins, Secretory » Protease Nexins » Amyloid beta-Protein Precursor
Description
A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES. MeSH
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Subtype Terms (1)
Amyloid beta-Peptides
3 drugs (2 approved, 1 experimental)
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