Phenomena and Processes [G] » Immune System Phenomena [G12] » Antigen-Antibody Reactions » Antigenic Modulation
Description
Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies. MeSH
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