Endothelial Growth Factors D016228

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » Endothelial Growth Factors

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » Endothelial Growth Factors

Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » Endothelial Growth Factors

Description

These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.   MeSH

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