Related MeSH Hierarchy (8)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Cell Adhesion Molecules » CD11 Antigens » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Cell Adhesion Molecules » Receptors, Lymphocyte Homing » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Cell Adhesion Molecules » CD11 Antigens » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Cell Adhesion Molecules » Receptors, Lymphocyte Homing » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Integrins » Receptors, Leukocyte-Adhesion » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Receptors, Lymphocyte Homing » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Cell Adhesion Molecules » CD11 Antigens » Lymphocyte Function-Associated Antigen-1
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Cell Adhesion Molecules » Receptors, Lymphocyte Homing » Lymphocyte Function-Associated Antigen-1
Description
An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1. MeSH
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