Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » RNA-Binding Proteins » Gene Products, rev
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nucleoproteins » RNA-Binding Proteins » Gene Products, rev
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Viral Regulatory and Accessory Proteins » Trans-Activators » Gene Products, rev
Description
Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. Rev is short for regulator of virion. MeSH
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