Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein-Tyrosine Kinases » src-Family Kinases » Oncogene Protein pp60(v-src)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Oncogene Proteins, Viral » Retroviridae Proteins, Oncogenic » Oncogene Protein pp60(v-src)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Oncogene Proteins, Viral » Retroviridae Proteins, Oncogenic » Oncogene Protein pp60(v-src)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Retroviridae Proteins » Retroviridae Proteins, Oncogenic » Oncogene Protein pp60(v-src)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein-Tyrosine Kinases » src-Family Kinases » Oncogene Protein pp60(v-src)
Description
A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. MeSH
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