Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » Transforming Growth Factors
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » Transforming Growth Factors
Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » Transforming Growth Factors
Description
Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. MeSH
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