Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Histocompatibility Antigens Class I » HLA-C Antigens
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Histocompatibility Antigens Class I » HLA-C Antigens
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Histocompatibility Antigens » Histocompatibility Antigens Class I » HLA-C Antigens
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Histocompatibility Antigens » HLA Antigens » HLA-C Antigens
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Isoantigens » Histocompatibility Antigens » Histocompatibility Antigens Class I » HLA-C Antigens
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Isoantigens » Histocompatibility Antigens » HLA Antigens » HLA-C Antigens
Description
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma). MeSH
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