Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Thyroid Hormones » Thyroxine
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Amino Acids » Amino Acids, Cyclic » Amino Acids, Aromatic » Thyroxine
Description
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. MeSH
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