Chemicals and Drugs [D] » Organic Chemicals [D02] » Amides » Lactams » beta-Lactams » Carbapenems » Thienamycins
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 2-Ring » beta-Lactams » Carbapenems » Thienamycins
Description
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors. MeSH
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