Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 2-Ring » Purines » Purine Nucleotides » Guanine Nucleotides » RNA Caps
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleic Acids » RNA » RNA, Messenger » RNA Caps
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleotides » Purine Nucleotides » Guanine Nucleotides » RNA Caps
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleotides » Ribonucleotides » Guanine Nucleotides » RNA Caps
Description
Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis. MeSH
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