Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Terpenes » Diterpenes » Retinaldehyde
Chemicals and Drugs [D] » Organic Chemicals [D02] » Aldehydes » Retinaldehyde
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Hydrocarbons, Acyclic » Alkenes » Polyenes » Carotenoids » Retinoids » Retinaldehyde
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Hydrocarbons, Cyclic » Hydrocarbons, Alicyclic » Cycloparaffins » Cyclohexanes » Cyclohexenes » Carotenoids » Retinoids » Retinaldehyde
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Terpenes » Carotenoids » Retinoids » Retinaldehyde
Chemicals and Drugs [D] » Biological Factors [D23] » Pigments, Biological » Carotenoids » Retinoids » Retinaldehyde
Description
A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. MeSH
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