Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Cinchona Alkaloids » Quinidine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Quinuclidines » Quinidine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 2-Ring » Quinolines » Quinidine
Description
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. MeSH
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