Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Ligases » Carbon-Carbon Ligases » Pyruvate Carboxylase
Description
A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1. MeSH
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