Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Pore Forming Cytotoxic Proteins » Antimicrobial Cationic Peptides » Polymyxins » Polymyxin B
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Antimicrobial Peptides » Antimicrobial Cationic Peptides » Polymyxins » Polymyxin B
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Macrocyclic Compounds » Peptides, Cyclic » Polymyxins » Polymyxin B
Chemicals and Drugs [D] » Lipids [D10] » Lipopeptides » Polymyxins » Polymyxin B
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Antimicrobial Cationic Peptides » Polymyxins » Polymyxin B
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptides, Cyclic » Polymyxins » Polymyxin B
Description
A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic. MeSH
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