Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Hydrocarbons, Cyclic » Hydrocarbons, Alicyclic » Cycloparaffins » Cyclohexanes » Picrotoxin
Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Terpenes » Sesquiterpenes » Picrotoxin
Chemicals and Drugs [D] » Organic Chemicals [D02] » Lactones » Picrotoxin
Chemicals and Drugs [D] » Complex Mixtures [D20] » Biological Products » Plant Preparations » Plant Extracts » Picrotoxin
Chemicals and Drugs [D] » Biological Factors [D23] » Toxins, Biological » Picrotoxin
Chemicals and Drugs [D] » Pharmaceutical Preparations [D26] » Plant Extracts » Picrotoxin
Description
A mixture of PICROTOXININ and PICROTIN that is a noncompetitive antagonist at GABA-A receptors acting as a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. MeSH
Hierarchy View
Hierarchy Tree View
YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.
