Lactase-Phlorizin Hydrolase D010694

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Glycoside Hydrolases » Galactosidases » beta-Galactosidase » Lactase » Lactase-Phlorizin Hydrolase

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Multifunctional Enzymes » Lactase-Phlorizin Hydrolase

Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Glycoside Hydrolases » Glucosidases » Lactase-Phlorizin Hydrolase

Description

A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N-acylsphingosine. The second domain (EC 3.2.1.108) hydrolyzes LACTOSE and is found in the intestinal brush border membrane. Loss of activity for this enzyme in humans results in LACTOSE INTOLERANCE.   MeSH

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