Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Parkinsonian Disorders » Parkinson Disease, Secondary » Parkinson Disease, Postencephalitic
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Parkinsonian Disorders » Parkinson Disease, Secondary » Parkinson Disease, Postencephalitic
Description
Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754) MeSH
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