Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Hydrocarbons, Cyclic » Hydrocarbons, Aromatic » Polycyclic Aromatic Hydrocarbons » Naphthacenes » Anthracyclines » Plicamycin
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Polycyclic Aromatic Hydrocarbons » Naphthacenes » Anthracyclines » Plicamycin
Chemicals and Drugs [D] » Carbohydrates [D09] » Glycosides » Aminoglycosides » Anthracyclines » Plicamycin
Description
A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies. MeSH
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