Chemicals and Drugs [D] » Lipids [D10] » Lipoproteins » Lipoproteins, LDL
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Lipoproteins » Lipoproteins, LDL
Description
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues. MeSH
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Subtype Terms (1)
Cholesterol, LDL
9 drugs (4 approved, 5 experimental)
Phase 1 Indicated Drugs (2)
Other Experimental Indicated Drugs (1)
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