Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Acyltransferases » Phosphatidylcholine-Sterol O-Acyltransferase
Description
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. MeSH
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