Langerhans Cells D007801

Related MeSH Hierarchy (4)

Anatomy [A] » Cells [A11] » Antigen-Presenting Cells » Dendritic Cells » Langerhans Cells

Anatomy [A] » Cells [A11] » Epithelial Cells » Dendritic Cells » Langerhans Cells

Anatomy [A] » Hemic and Immune Systems [A15] » Immune System » Antigen-Presenting Cells » Dendritic Cells » Langerhans Cells

Anatomy [A] » Hemic and Immune Systems [A15] » Immune System » Mononuclear Phagocyte System » Dendritic Cells » Langerhans Cells

Description

Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.   MeSH

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