Related MeSH Hierarchy (7)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Fragments » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Immunoglobulin Variable Region » Immunoglobulin Joining Region
Description
A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM. MeSH
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