Related MeSH Hierarchy (7)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Fragments » Immunoglobulin Fragments » Immunoglobulin Idiotypes
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Idiotypes
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Idiotypes
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Idiotypes
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Epitopes » Immunoglobulin Idiotypes
Phenomena and Processes [G] » Chemical Phenomena [G02] » Biochemical Phenomena » Molecular Structure » Amino Acid Sequence » Immunoglobulin Variable Region » Immunoglobulin Idiotypes
Phenomena and Processes [G] » Immune System Phenomena [G12] » Immunogenetic Phenomena » Immunoglobulin Idiotypes
Description
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains. MeSH
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