Globosides D005915

Related MeSH Hierarchy (4)

Chemicals and Drugs [D] » Organic Chemicals [D02] » Amides » Ceramides » Globosides

Chemicals and Drugs [D] » Carbohydrates [D09] » Glycoconjugates » Glycolipids » Glycosphingolipids » Neutral Glycosphingolipids » Ceramides » Globosides

Chemicals and Drugs [D] » Lipids [D10] » Glycolipids » Glycosphingolipids » Neutral Glycosphingolipids » Ceramides » Globosides

Chemicals and Drugs [D] » Lipids [D10] » Membrane Lipids » Sphingolipids » Glycosphingolipids » Neutral Glycosphingolipids » Ceramides » Globosides

Description

Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.   MeSH

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