Dianhydrogalactitol D003961

Chemicals and Drugs [D] » Organic Chemicals [D02] » Alcohols » Sugar Alcohols » Galactitol » Dianhydrogalactitol

Chemicals and Drugs [D] » Carbohydrates [D09] » Sugar Alcohols » Galactitol » Dianhydrogalactitol

Description

One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.   MeSH

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