Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Macrocyclic Compounds » Peptides, Cyclic » Cyclosporins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptides, Cyclic » Cyclosporins
Description
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection. MeSH
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