Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Enzyme Inhibitors » Cholinesterase Inhibitors
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Neurotransmitter Agents » Cholinergic Agents » Cholinesterase Inhibitors
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Physiological Effects of Drugs » Neurotransmitter Agents » Cholinergic Agents » Cholinesterase Inhibitors
Description
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. MeSH
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Phase 4 Indicated Drugs (3)
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