Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Membrane Transport Modulators » Calcium Channel Agonists
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Physiological Effects of Drugs » Calcium-Regulating Hormones and Agents » Calcium Channel Agonists
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Therapeutic Uses » Cardiovascular Agents » Vasoconstrictor Agents » Calcium Channel Agonists
Description
Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture. MeSH
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