Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Beta-Globulins » beta 2-Microglobulin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Beta-Globulins » beta 2-Microglobulin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Histocompatibility Antigens Class I » beta 2-Microglobulin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Histocompatibility Antigens Class I » beta 2-Microglobulin
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Histocompatibility Antigens » Histocompatibility Antigens Class I » beta 2-Microglobulin
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Isoantigens » Histocompatibility Antigens » Histocompatibility Antigens Class I » beta 2-Microglobulin
Description
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants. MeSH
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