Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Antigens, Viral » Antigens, Viral, Tumor » Antigens, Polyomavirus Transforming
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Oncogene Proteins, Viral » Antigens, Polyomavirus Transforming
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Oncogene Proteins, Viral » Antigens, Polyomavirus Transforming
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Neoplasm » Antigens, Viral, Tumor » Antigens, Polyomavirus Transforming
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Viral » Antigens, Viral, Tumor » Antigens, Polyomavirus Transforming
Description
Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle. MeSH
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