Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Macrocyclic Compounds » Peptides, Cyclic » Amanitins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Oligopeptides » Amanitins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptides, Cyclic » Amanitins
Chemicals and Drugs [D] » Biological Factors [D23] » Toxins, Biological » Mycotoxins » Amanitins
Description
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals. MeSH
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