Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Alkylating Agents
Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Toxic Actions » Noxae » Alkylating Agents
Description
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. MeSH
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