Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Variation » Phase Variation
Description
An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises through rapid reversible mutations in the glpK gene through phase variation. MeSH
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