Anatomy [A] » Cells [A11] » Cellular Structures » Intracellular Space » Cell Nucleus » Cell Nucleus Structures » Intranuclear Space » Nuclear Bodies » Promyelocytic Leukemia Nuclear Bodies
Description
Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes. MeSH
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