Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Organic Chemicals [D02] » Aza Compounds » Azacitidine » Decitabine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, 1-Ring » Pyrimidines » Pyrimidine Nucleosides » Cytidine » Azacitidine » Decitabine
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleosides » Pyrimidine Nucleosides » Cytidine » Azacitidine » Decitabine
Chemicals and Drugs [D] » Nucleic Acids, Nucleotides, and Nucleosides [D13] » Nucleosides » Ribonucleosides » Cytidine » Azacitidine » Decitabine
Description
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA. MeSH
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Phase 2 Indicated Drugs (2)
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