Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Peptide Hormones » Progranulins » Granulins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » Progranulins » Granulins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intercellular Signaling Peptides and Proteins » Progranulins » Granulins
Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » Progranulins » Granulins
Description
Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc. MeSH
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