Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Inhibitor of Apoptosis Proteins » Survivin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Cell Cycle Proteins » Survivin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Cytoskeletal Proteins » Microtubule Proteins » Microtubule-Associated Proteins » Survivin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Apoptosis Regulatory Proteins » Inhibitor of Apoptosis Proteins » Survivin
Description
An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA. MeSH
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