Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » GPI-Linked Proteins » CD52 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » GPI-Linked Proteins » CD52 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Neoplasm » CD52 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Biomarkers » Antigens, Differentiation » CD52 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Lipid-Linked Proteins » GPI-Linked Proteins » CD52 Antigen
Description
A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB). MeSH
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