Chemicals and Drugs [D] » Biological Factors [D23] » Intercellular Signaling Peptides and Proteins » Apelin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intercellular Signaling Peptides and Proteins » Apelin
Description
A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response. MeSH
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