Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Lectins » Lectins, C-Type » Pancreatitis-Associated Proteins
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Neoplasm » Pancreatitis-Associated Proteins
Chemicals and Drugs [D] » Biological Factors [D23] » Biomarkers » Biomarkers, Tumor » Pancreatitis-Associated Proteins
Description
C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker. MeSH
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