Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » RNA-Binding Proteins » RNA Splicing Factors » PTB-Associated Splicing Factor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » DNA-Binding Proteins » PTB-Associated Splicing Factor
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nucleoproteins » RNA-Binding Proteins » RNA Splicing Factors » PTB-Associated Splicing Factor
Description
An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS. MeSH
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