Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Deubiquitinating Enzymes » Ubiquitin-Specific Proteases » Tumor Necrosis Factor alpha-Induced Protein 3
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Endopeptidases » Ubiquitin-Specific Proteases » Tumor Necrosis Factor alpha-Induced Protein 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Tumor Necrosis Factor alpha-Induced Protein 3
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Ligases » Ubiquitin-Protein Ligase Complexes » Ubiquitin-Protein Ligases » Tumor Necrosis Factor alpha-Induced Protein 3
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Tumor Necrosis Factor alpha-Induced Protein 3
Description
A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity. MeSH
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