Epithelial Cell Adhesion Molecule D000071858

Related MeSH Hierarchy (4)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Cell Adhesion Molecules » Epithelial Cell Adhesion Molecule

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Cell Adhesion Molecules » Epithelial Cell Adhesion Molecule

Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Neoplasm » Epithelial Cell Adhesion Molecule

Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Cell Adhesion Molecules » Epithelial Cell Adhesion Molecule

Description

A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.   MeSH

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