Organisms [B] » Viruses [B04] » RNA Viruses » Negative-Sense RNA Viruses » Orthomyxoviridae » Influenzavirus A » Influenza A virus » Influenza A Virus, H5N8 Subtype
Description
A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses. MeSH
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