Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Signaling Lymphocytic Activation Molecule Family » CD48 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » GPI-Linked Proteins » CD48 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » Signaling Lymphocytic Activation Molecule Family » CD48 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Lipid-Linked Proteins » GPI-Linked Proteins » CD48 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » GPI-Linked Proteins » CD48 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Signaling Lymphocytic Activation Molecule Family » CD48 Antigen
Description
A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response. MeSH
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