API | xl228

xl228 Report issue

Small molecule Experimental

AACT ChEMBL DrugBank PubChem

Active Ingredient History

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Chemistry

SMILES: CC(C)c1cc(CNc2nc(Nc3cc(C4CC4)[nH]n3)cc(N3CCN(C)CC3)n2)on1
InChIKey: ALKJNCZNEOTEMP-UHFFFAOYSA-N
Mol. Mass: 437.55
ALogP: 3.3 Partition coefficient
ChEMBL Molecule:
xl-228

More Chemistry

Pharmacology

Mechanisms of Action:
- Insulin-like growth factor 1 receptor (Homo sapiens) ^UniProt
- Tyrosine-protein kinase ABL1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

xl228 | xl-228

Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (4)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (4)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 1)

Lymphoma (Phase 1)

Neoplasms (Phase 1)

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Phase 1)

Overview

Highest Phase: Phase 1
# of Trials: 2
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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