valbenazine (ingrezza) Report issue

Small molecule Approved FDA Fast Track FDA Priority Review FDA
AACT ChEMBL DrugBank Drugs@FDA MeSH PubChem

Active Ingredient History

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  • Now
Valbenazine, sold under the brand name Ingrezza, is a medication used to treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor.   Wikipedia

Chemistry

  • SMILES: COc1cc2c(cc1OC)[C@H]1C[C@@H](OC(=O)[C@@H](N)C(C)C)[C@H](CC(C)C)CN1CC2.Cc1ccc(S(=O)(=O)O)cc1.Cc1ccc(S(=O)(=O)O)cc1
  • InChIKey: BXGKAGLZHGYAMW-TZYFFPFWSA-N
  • Mol. Mass: 762.99
  • ALogP: 3.56
  • ChEMBL Molecules:
    valbenazine tosylate  
    valbenazine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: Yes

Drug Pricing (per unit)

United States

$145.1160 - $207.4890
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

ingrezza | mt-5199 | nbi-98854 | valbenazine | valbenazine tosylate | valine 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2h-benzo(a)quinolizin-2-yl ester

Organizations (12)

Research & Development (7)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (16)

Approved Indications (1)


 

Tardive Dyskinesia

Experimental Indications - Clinical Trial Phases 1-4 (16)


 

Bipolar Disorder (Phase 4)

Cerebral Palsy (Phase 3)

Depressive Disorder, Major (Phase 4)

Dermatology (Phase 4)

Developmental Disabilities (Phase 4)

Dyskinesias (Phase 3)

Healthy Volunteers (Phase 1)

Huntington Disease (Phase 3)

Intellectual Disability (Phase 4)

Pharmacological and Toxicological Phenomena (Phase 1)

Psychotic Disorders (Phase 4)

Schizophrenia (Phase 4)

Tardive Dyskinesia (Phase 4)

Torticollis (Phase 4)

Tourette Syndrome (Phase 2)

Trichotillomania (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 30
  • # of Trial Organizations: 7

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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