Active Ingredient History

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Imagabalin was an investigational drug that acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, with some selectivity for the α2δ1 subunit over α2δ2. It was under development by Pfizer as a pharmaceutical medication due to its hypothesized anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. It reached phase-III clinical trials for treatment of generalized anxiety disorder; however, the trials were terminated by the manufacturer. The drug is no longer under development.   Wikipedia

  • SMILES: CCC[C@@H](C)C[C@H](N)CC(=O)O
  • InChIKey: JXEHXYFSIOYTAH-SFYZADRCSA-N
  • Mol. Mass: 173.26
  • ALogP: 1.61
  • ChEMBL Molecule:
More Chemistry
imagabalin | pd 0332334 | pd-0332334 | pf-00195889

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